The leading and trusted non-invasive prenatal screening test using the latest advances in DNA technology. Enhancing existing prenatal screening pathways for pregnant women with fast, reliable results and reducing the need for invasive tests and the associated stress and anxiety.
The Neuberg IONA® test is a non-invasive prenatal test (NIPT) for pregnant women which estimates the risk of a fetus having Down’s syndrome or some other serious genetic diseases. The Neuberg IONA® test is an advanced screening test that is carried out on a small maternal blood sample. Pregnant women can expect test results from their healthcare provider within approximately 3-5 days from sample receipt.
The Neuberg IONA® test estimates the risk of a fetus having Down’s syndrome (Trisomy 21), Edwards’ syndrome (Trisomy 18) and Patau’s syndrome (Trisomy 13). Trisomies occur when three, instead of the usual two, copies of a chromosome are present. Edwards’ and Patau’s syndromes are much rarer than Down’s but are very serious and many affected babies do not survive
During pregnancy the placenta leaks cell-free DNA which circulates in the maternal bloodstream. As a result, a maternal blood sample contains a mixture of foetal and maternal circulating DNA. The IONA® test directly measures the amount of this cell-free DNA and can detect small changes in the DNA ratio between the maternal and cell-free DNA when a foetal trisomy 21, 18 or 13 is present.
Traditional first trimester screening offered during pregnancy is called the First Trimester Combined Test (FTCT). This is an ultrasound scan to measure the nuchal translucency (NT) and a blood test. This method is less accurate for detecting foetal aneuploidies (85-90%), but can help with the early detection of both maternal and foetal complications. The IONA® test is the only NIPT that has the option to incorporate the result of the FTCT into the calculation to offer you the most comprehensive and tailored prenatal screen.
You can still get accurate trisomy screening even without the FTCT result. Many women choose to have an IONA® test from 10 weeks gestation following an ultrasound, which is an essential requirement for Neuberg IONA®.
The IONA® test has a higher detection rate than the current FTCT offered to pregnant women. This means that fewer pregnant women will undergo unnecessary invasive follow-up procedures such as amniocentesis or CVS* which can be stressful, painful and may carry a small risk of miscarriage.
The leading and trusted non-invasive prenatal screening test using the latest advances in DNA technology. Enhancing existing prenatal screening pathways for pregnant women with fast, reliable results and reducing the need for invasive tests and the associated stress and anxiety.
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